Author: lisajericho

CBD Oil In Canada – Why Thousands Are Flocking To Brands Like Elixinol

Canada is a place where one can find a huge variety of different cannabis and hemp products in every town.

More and more people are becoming interested in reaping the benefits of CBD oils. If you are such a person and you are looking for something to give you appetite, cure insomnia, or to reduce anxiety or pain, the Elixinol CBD oil is one of the few premium quality CBD oils available to you in the US.

Elixinol CBD oil has a number of benefits that will definitely excite you. Read on to find out everything you need to know about Elixinol so that you can make an informed decision on whether or not to buy.

About Elixinol and products

Elixinol is one of the most popular CBD oil manufacturing companies in the states. It is based in Colorado and boasts superior extraction and purification equipment.

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Alongside its CBD oils, the company has a variety of other products including hemp protein, hemp seeds, flavored hemp oil tinctures, capsules and a special applicator.

What sets the company apart?

  1. The company sources the best-grade industrial hemp

The founder, Paul Benhaim, has been involved in the hemp plant business for over two decades. He knows the real growers and gets his product only from the best of the best.

  1. Elixinol has quality control mechanisms

Unlike other hemp processing companies, Elixinol has several in-house and external quality control staff who help to ensure that the hemp raw materials received meet all the set quality requirements.

  1. Pharmaceutical-grade manufacturing and testing

The company has high-grade equipment for extracting and processing hemp CBD extract into oils. The company also has lab machines for testing the quality, potency, and concentration of CBD in their oils before the final packaging and shipping to stores and customers.

Buying CBD Oil In Canada

If you want to buy CBD oil in Canada, make sure to do your research online beforehand.

Vancouver and Toronto have both seen a huge increase in CBD shops over the past couple years.

There has been an emerging cannabis oil movement in these areas known as CBD oil Canada.

Buying cannabidiol products online allows you to access certain discounts you might not get elsewhere.

Many Canadian residents have gotten big discounts by ordering online.

This country really loves the high-quality CBD brands.

  1. Transparency

Elixinol is an advocate for the accurate labeling of CBD products. They believe in providing a full list of the ingredients in all their products. This ensures that customers know exactly what they are buying.

  1. The owner of the company is known

The founder of the company, Paul Benhaim, is a relatively popular figure in the wellness scene. At the very least, the fact that people trust him is an indicator that his products work.

Top Elixinol CBD Oil Products

  1. Hemp CBD oil tinctures

This is perhaps the most potent Elixinol CBD oil of them all. It is available in two flavors: natural and cinnamint.

The tinctures come in exciting blue bottles complete with 1ml droppers. Each bottle includes the full range active cannabinoids (except THC) to ensure you reap all the healing benefits!

Unlike other CBD oils, this one is made of a light tincture to enable optimum absorption for maximum potency.

The tinctures are available in two sizes. There is an average 30ml bottle with a CBD concentration of 300mg and a bigger 120ml bottle with a ten times stronger CBD concentration of 3600mg.

  1. Elixinol CBD capsules

Elixinol’s capsules are the solid versions of the company’s CBD oil tinctures.

Just like the oils, the capsules are made from superior quality CBD hemp extract using the latest manufacturing technologies.

You will love the fact that there are two bottles. A bigger 900mg bottle and a smaller and cheaper 450mg bottle. The big bottle contains 60 CBD capsules, while the smaller one has 30.
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Each of the capsules contains a high-potency concentration of cannabinoids.

The interaction between the CBDs and your body’s endocannabinoid system can reduce pain, inflammation, stress, muscle tremors, and could even bring back your appetite.

The manufacturer advises users to take one capsule daily as a nutritional supplement to realize these many benefits.

  1. Elixinol CBD oil Liposomes (Sprays)

Elixinol’s oil liposomes are some of the cheapest CBD sprays available on the market. The sprays deliver CBD faster into your system than oils and capsules. This makes them the best option for those who want to instantly feel the effects of CBD.

There are two bottles available, a designer 300mg bottle with citrus flavor and its bigger 1000mg version that also comes in citrus flavor.

The spray bottles are spill-proof ensuring maximum use and can deliver up to 5mg concentrate of CBD per spray.

What’s unique about Elixinol’s spray is that its CBD is contained in microscopic liposomes. This ensures maximum bioavailability. Liposomes pass through cell walls faster than oils. This allows for 100% CBD delivery to cell receptors and other components of the body’s endocannabinoid system.

  1. Elixinol lip balm

Elixinol’s lip balm is one of the most innovative CBD products you will find online.

It is specially formulated with natural CBD hemp extract, omega oils and vitamin E for use on the lips.

The natural formula will nourish and rejuvenate dry lips and protect them from the elements.

  1. X-pen

There are CBD bottles, droppers, and capsules and then there is the X-Pen.

The X-pen is a special applicator developed by Elixinol for the precise delivery of CBD. The pen is hygienic, prevents spillage, delivers precise quantities of CBD and keeps its contents in a vacuum away from bacteria.

This keeps CBD fresh and allows you to enjoy precisely 15mg of CBD per click/ serving.

What are the known benefits of Elixinol’s hemp-extracted CBD oils?

Elixinol’s hemp-extracted CBD oils have a variety of benefits. Even though the company states that its products should only be used as nutritional supplements and not as medicines, hemp cannabinoids are known to have a variety of medicinal benefits including:

  • Alleviating pain
  • Reducing anxiety and depression
  • Increasing appetite
  • Reducing insomnia
  • Improving skin health
  • Reducing the frequency of seizures

There are many more benefits that are not listed as the company does not operate as a pharmaceutical company but as a nutritional supplements company.

Research is still ongoing on other benefits of CBD oils.

CBD Oil In Toronto

Many Toronto residents love CBD a lot.

People are ordering it in droves.

Elixinol is an American-based company but also loves Canada. It has quality assurance processes to ensure the products reaching its clients are of the highest quality and potency.

It also has state of the art manufacturing equipment to guarantee safe and hygienic extraction and packaging of CBD oils.

The tinctures, capsules, the liposomes and the X-pen provide clients with multiple ways to consume CBD in Toronto.

The mayor probably likes it too.

There are also several flavors and quantities available giving customers more options to choose from.

In conclusion, Elixinol is a solid manufacturer with a wide variety of quality products. You should definitely give them a shot.

Check out their products by visiting the official Elixinol webshop here.

CBD Oil For Multiple Sclerosis – How It Helps, Best Practices, and More

What is multiple sclerosis?

This is a condition that adversely affects the brain and the central nervous system. Women are more susceptible to the condition compared to men. It is more common to people aged between 15 to 60 years. The symptoms associated with the disease varies from one person to another depending on the body nerves that are affected. The late stage of the disease may cause total body paralysis. The disease has no cure but the management is aimed at prevent further deterioration.

The symptoms of the disease include:

• partial or permanent visual impairment- occurs to one eye at a time
• sharp pains in various parts of the body
• Baber chair symptoms where sudden sensations travel from neck to the spine.
• Prolonged Increased body fatigue
• Dizziness
• Numbness
• Mood swings
• Bladder disfunction and pains in the bowel
• Dysarthria which leads to slow speech
• Unstable walking style

Causes of multiple Sclerosis

The cause of the disease is unknown. However, researchers link the cause condition to the immune system attacking central nervous system. The immune system is said to destroy myelin which is the enclosing safety cover of the nerves fiber ensuring a seamless communication between the brain and other parts of the body. This condition causes the nerves to be weak and can cause permanent damage. Certain factors accelerate the risk of one getting infected, among them include:

• Smoking- smokers exhibit more chances of getting the disease.
• Climatic condition- the disease is more common in countries where climate is temperate like New Zealand, Canada, south eastern Australia and Europe.
• Demography-It is common to people from northern Europe and rare to people in Africa and Asia.
• Certain viruses accelerate the likelihood of one getting infected like the Epstein-Barr virus.
• Genealogical history- more prevalent to families with history of the infection
• Immune disorders- people with immune system disorders have a high chance of contracting multiple sclerosis. such disorders include thyroid diseases.
• Multiple sclerosis may cause other fatal conditions. They include:
• Body muscles becomes rigid
• May lead partial and complete paralysis
• May lead to epilepsy
• May lead to depression
• May reduce mental capacity among many other effects

How is multiple sclerosis treated?

This disease is treated through differential diagnosis. This is the only way since multiple sclerosis does not have a specific medical test. Several treatment options are available, among them being:
• Physical therapy
This is mostly used for patients who portrays symptoms of disabled mobility, this helps in strengthening the affected muscles.
• Muscle relaxants
This is the kind of medication preferably used to the people with symptoms of sudden muscle contractions especially in the legs. Most commonly used drug is baclofen.
• Use of fatigue relievers
• Use of CBD oil

What is CBD oil?

This has drawn attention in the field of medicine. CBD oil is one of the 2 major compounds extracted from the cannabis plant. The other compound is tetrahydrocannabinol (THC). Due to the believe that is held by people towards the use of cannabis and cannabis products, that it has psychoactive elements, CBD products have been generally frowned upon for long. People have mixed reactions on the substance. For this reason, the manufacture and use of CBD oil is illegal in many parts of the world.

How CBD works

When CBD oil is taken, it affects the endocannabinoid system receptors which maintain stable body homeostasis. They affect both CB1 and CB2 receptors. CB1 receptors are responsible for maintaining good brain and nervous system health. CB2 receptors enhance the immune system.

The CB1 and CB2 receptors are triggered by the activity of the body cannabinoids. They increase the production of the natural cannabinoids. This leads to enhanced activity of the endocannabinoid system which in turn enhances the healing cycle. CBD oil is not psychoactive and this means it has no effect to the brain as THC does. CBD has been proven to be effective for number of uses in the body. They include:

• Helps to fight nausea and vomiting
• Has anti-inflammatory effects
• Reduces seizure
• Prevents cancer
• Helps fight anxiety
• Has pain relieving ability

How CBD oil Treats Multiple Sclerosis

The cannabinoid compound in the CBD oil is the one responsible for the healing effect. The human body secretes its own cannabinoids from the brain. The body has cannabinoids receptors located in almost every part the body but they have higher concentration in the hippocampus, cerebral cortex, cerebellum, basal ganglia, hypothalamus and amygdala. These are the CB1 receptors. The receptors are mostly found in the brain and they affect movement, pain, emotions, moods, cognitive abilities, appetite, memory among other functions.

The other receptors associated with cannabinoids are CB2 receptors. They are linked to the immune system and they are responsible for inflammation and pain. These CB2 receptors when activated by CBD oil helps in the healing process.

The various research done in the field of medicine has demonstrated CBD oil’s ability to heal multiple Sclerosis by preventing further damage to the central nervous system.
Research by Research Institute of Neurochemistry demonstrated that CBD oil alleviates both trauma caused by shock or brain injury and neurodegeneration. Another support research published by Future Medicinal Chemistry revealed that CBD oil’s interaction with CB2 receptors suppress immunosuppression that is caused by multiple Sclerosis. All these activities enhance suppression of the symptoms due multiple sclerosis.

The Ideal Dosage of CBD for Multiple Sclerosis

The symptoms vary from one patient to another and also CBD oils react differently among different patients. It is for these reasons that a doctor’s prescription is recommended before taking CBD oil. Medics also determine the right dosage by first giving a small dosage and increasing it with time while monitoring the progress.

The Main Take Away

CBD oil medicinal benefits cannot be ignored since time and again research has proven its long list of healing abilities. Despite all these, it is still illegal in some parts of the world. Its benefits cannot be ignored. On multiple sclerosis management, CBD oil has been proven that it helps improves the endocannabinoid system by enhancing the receptors in the immune system. However, it’s good to seek medical attention to get the right dosage to avoid the side effects associated with CBD oil. MS in Europe is working to spread the word on Cannabidiol and all of its benefits for people with this disease.

How CBD Oil Helps The Symptoms Of Multiple Sclerosis

They constantly think out of the box because until today, the cannabis industry is still undergoing rapid changes through the years and one has to keep up with all these changes if you want to stay relevant and more so respected in a market that is swarming with competitions.

The makers understand the science of cannabis itself and stay glued to the fundamentals while at the same time innovating without compromising genetics, quality, and performance. Multiple Sclerosis (MS) can be greatly assisted by CBD oil products. People with MS in Europe are flocking to this remedy to improve their own lives.

What sets them even more apart from the rest is that they take customer feedback seriously. They take each feedback to heart and listen to both praises and criticisms with the goal of improving their products so it meets people’s expectations. 4 Corners is also active in social media seeing this is the most widely used and cost-effective platform today. They know how to use technology to their advantage and reach out to people and at the same time, market their product and not only to listen to their customers concerns.

The symptoms of Multiple Sclerosis include pain, numbness, weakness, and other disabilities. European residents are working together to solve their MS with CBD oil.

When you do decide to order from them, they ship your order right away within the first 24 hours of placing your order. They charge a flat rate shipping fee of $5 in delivering your package that looks so discrete nobody would suspect it has cannabis inside it. They safeguard your privacy and will ship it to you wherever you are in the world a.k.a. the four corners of the planet. If you are in the US, though, your CBD is delivered to your doorstep in 2-3 days and you can use it as prescribed or according to your own preferences. You won’t be judged, as if using CBD is that much of a big deal right now when even doctors and other health experts prescribe or openly endorse it. There is no more shaming (or rather less shaming) involved with CBD seeing how beneficial it is to human health. It has made a big impact to the lives of countless patients suffering from various ailments and we are just thankful we have one company here that we can always count on to give us superior quality CBD that is as good as anybody can get.

The Pharmacology Of Kratom Explained

 

What is the pharmacology of kratom?

Kratom is a plant that originated from Southeast Asia and Thailand. It has been used to treat opioid withdrawal, cough, diarrhea, and pain in Asia. It is due to these benefits that kratom is becoming popular especially in the field of medicine. This Wiki page is replete with info on Mitragyna Speciosa.

kratom powder in bowl with leaves

The primary active substances in kratom are mitraphylline, mitragynine, and 7-hydroxymitragynine. Others less active chemicals include: raubasine, corynanthidine, rhynchophylline, and many others. The location of the kratom trees determines the composition of the active chemicals. For instance, the level of active compounds is very high in trees grown in Southeast Asia. The levels are low in trees grown in other areas, greenhouses included.

Pharmacology

The mode of action of kratom is similar to that of an opioid receptor agonist. When compared to the traditional opiates, its effects and pharmacological actions tend to differ significantly. On the mu receptors, mitragynine and 7-hydroxymitragynine bind as partial agonists. On the kappa and delta receptors, they act as an antagonist. Their binding affinities are high in mu and kappa receptors. Kratom also has an affinity for norepinephrine, serotonin, and kappa, unlike the other opioids. The kratom’s stimulating properties are as a result of activation of serotonin and norepinephrine.

 

king-amazon-green-2 kratom forever tree

  • Mitragynine

It is the most abundant active alkaloid in the Mitragyna speciosa. 1.2% to 2.1% of the compound is contained in the dried kratom’s leaves.  It is involved in the improvement of mood and has analgesic effects. It also promotes relaxation and stimulation. It acts on mu-opioid receptors. When oxidized, a product called mitragynine pseudoindoxyl is formed. This product works as a selective mu-opioid agonist and has reduced affinity for both kappa and delta receptors. In chronic users, mitragynine has been put under extensive studies. Its metabolism takes place in the liver. it has linear kinetics, and its half-life is long.

Structure

Mitragynine has a molecular weight of 398.503g/mol. Its molecular formula is C23H30N204.

Properties

It exists as a white amorphous powder. At 235 degrees Celsius and 5 mm of mercury, the compound boils. It has a melting point of 104 degrees Celsius. The substance is soluble in organic compounds such as chloroform, alcohol, acetic acids, and many others.

Body fluids detection

The method of detection is referred to as liquid chromatography-mass spectrometry. People using kratom for recreational purposes have a mitragynine concentration of between 10 and 50 micrograms per liter in their blood.

 

Absorption, distribution, and excretion

On rats, a study was conducted. An oral dose of 20mg/kg of mitragynine was administered to each rat. At the end of the study period, it was observed that the mean plasma concentration was 424ng/ml. The time needed to reach the maximum plasma concentration was found to be 1.26 hours. The elimination half-life was 3.85 hours. 6.35l/hr./kg was the apparent total clearance. Finally, the apparent volume of distribution was 37.90l/kg.

Metabolism and its metabolites

Using Liquid Chromatography-Tandem Mass Spectrometry, mitragynine, paynantheine and speciogynine were found present in rats and human’s urine. Apart from mitragynine and speciogynine, other isomeric substances were detected. The urine of the kratom users was further screened to determine the phase I and II of the speciogynine. It was found that due to its retention times and mass spectra, the speciogynine and its metabolites were hard to identify in human urine. In phase I, seven metabolites were identified. They suggested that mitragynine underwent metabolism through hydrolysis of the methyl ester occupying position 16, O-demethylation of the 9-methoxy group and 17-methoxy group via the intermediate aldehydes by decreasing to alcohols or oxidation to carboxylic acids.

  • 7-hydroxymitragynine

7-hydroxymitragynine is a terpenoid indole alkaloid extracted from Mitragyna speciosa. On the mu receptors, 7-hydroxymitragynine acts as an agonist. It has a potency that is thirty-fold high as compared to mitragynine. Morphine has a strength that is 17-fold lower than that 7-hydroxymitragynine. The compound is associated with fewer side effects as compared to morphine.

Benefits

  • It is an opioid agonist. An opiate effect is felt when it reacts with the opioid receptors. The effect is essential in relieving pain.
  • It possesses a relaxing effect. When in high doses, 7-hydroxymitragynine provides a sedative and relaxing effects.
  • It brings about euphoria. Euphoria is felt when kratom is used in low doses. The euphoric effect makes kratom an alternative recreational drug.

Structure

Its molecular formula is C23H30N2O5. It has a molecular weight of 414.502g/mol.

Dosing

Factors such as health, age, body size and others determine the required dose. There is no specific dosage provided thus one should follow the directions on the product label. One can consult a healthcare provider. For safety purposes, it is recommended that one should avoid taking kratom regularly and in high amounts. No standardization and quality control in regulating the production and sale of kratom, therefore coming up with a standard dosage is quite challenging.

 

Kratom’s drug interaction

Combination of kratom with other drugs results in adverse drug interactions. The interaction is because some drugs share the same pharmacological properties with kratom. For instance, combining opiates and kratom is not recommended. This is to avoid synergy due to drug interaction, leading to over-sedation and respiratory depression.

https://www.webmd.com/mental-health/addiction/news/20160919/what-is-kratom-dea-ban#1

 

Conclusion

Kratom is extensively being used for both recreational and medical purposes. This due to the many benefits that it is associated with. A variety of active compounds are abundantly found in kratom as research suggest. These compounds are associated with the production of significant pharmacological effects at the opioid receptors. Kratom also has similar pharmacology as compared to other prescription opiates.

They are partial agonists and thus are associated with few side effects unlike other opiates, which are full agonists. Kratom just like other drugs is metabolized in the liver. Due to similar pharmacology, kratom tends to interact with other medications. Therefore, one should avoid combining it with other medicines. On the hand, one can seek the advice from a medical officer on the effectiveness and safety of combining kratom with other drugs. As a general rule, always avoid taking kratom in large doses. To reduce the chances of developing the side effects Kratom should not be used frequently.

 

How Buying Kratom Can Boost Your South African Metabolism

Multiple Sclerosis sufferers have been wanting to use Kratom for a variety of benefits lately. That is why MS In Europe decided to cover this specific topic.

Metabolism is the chemical process that happens within your system that maintains the life of your cells. Metabolism largely depends on nutrition and constant supply of nutrients. The production of energy is a vital process in the way that metabolism takes the course. On the same note, energy production also depends on catalysts. Scientific research reveals that Kratom speeds up energy production by catalyzing the nutrients’ absorption. Some metabolic activities include:

  • Respiration
  • Energy production
  • Nutrients absorption
  • Cell-division
  • Bodybuilding
  • Elimination of nitrogenous wastes

For metabolism to happen efficiently, there needs to be enough nutrients in your system. That insinuates that a balanced diet is a key to metabolism.  The good news about Kratom is that apart from adding fiber to your diet, it also plays a big role in making other nutrients work efficiently in the body. Two decades ago, a group of specialists found out that Kratom can turn out to add nutritional value to the usual diet. That led to the current observations of the chemical compounds of the herb.

How-To-Use-Kratom

Today, viable evidence on the alkaloids of this unique plant explain that the leaves have a chemical structure that benefits humanity in numerous ways. The different parts of the tree provide more than 40 components that contribute to the well being of humanity across the globe.

The use of Kratom in the right proportions brings noticeable improvement in the process of digestion to those who experience constipation. With that in mind, if you take Kratom with food, digestion runs smoothly, and the body absorbs the nutrients faster. Consequently, energy production flows more instantly compared to when the food gets into the digestive system without the components of the herb.

The efficient production of energy that results from smooth absorption of nutrients enables some of the body processes that require energy like cell division to go on much easier. So, in the case of body repairing process like the healing of wounds, Kratom contributes significantly.

Another remarkable method of taking this herb is through tea. It is simple to prepare Kratom tea, and it takes relatively little time. Out of all the methods devised to take the herb, this particular one seems to be the most efficient one. That is because you take it with water and additionally, it dissolves perfectly in relatively high temperatures.

It’s true that taking Kratom with other beverages like juice is also a good option but the tea made from the herb surpasses this because you enjoy it naturally. Since the herb reaches the digestive system in liquid form, it is absorbed conveniently. That makes it reach the bloodstream faster and combine with other nutrients to bring a stable supply of nutrients to the system.

How To Buy Kratom In South Africa

Many South Africans are looking to buy Kratom.

Traditionally, many people used the herb to cure diarrhea. Mostly, the cause of this condition is food poisoning or taking dirty foods. For years Kratom has hugely helped to curb this condition by strengthening the immune system by boosting the white blood cells production.

If you purchase Kratom online from any of the shops near Pretoria or Cape Town, you are really going to get a discount.

That way, the antibodies produced by the system to fight diarrhea syndrome multiply fast. The result is that the condition gets a defeat from the immune system.

People that use coupon codes when purchasing obviously save money.

Due to the medicinal capability of the herb, the ancient Thai’s as well as those who lived along the swampy jungles of Southeast Asia where kratom grew naturally, used it to fight several health conditions such as diabetes and post-traumatic disoders. Currently, the herb helps to fight diarrhea and enable the body to restore the water that it loses due to the dehydration caused by diarrhea.

A scenario that further explains the importance of Kratom in the body system is whereby some medication related to opiates comes in. Opiates bring numerous side effects to the body. That is to say, that is to say, that they tamper with the body functionality which involves metabolism. On the other hand, Kratom medication when taken in accordance to the right doses enables the body system to run in a balanced way without adding side effects.

For nutrients to get into the body system, they must go through digestion. Breaking down of the nutrients does not end there; they are further broken down into much simpler compounds for the body to absorb them with ease. Lactose intolerance is a condition whereby a natural sugar called lactose fails to break down. The properties of Kratom facilitate the breakdown of food nutrients, and with the herb in your diet, lactose intolerance becomes a story to tell.

Kratom leaves_static_block

Kratom in normal cases, when taken in the right doses, helps in the digestion of food by slowing the movement of food through the gut. The gut comprises of the whole digestive channel. That is from the mouth to the rectum. Food passing through the digestive channel at a low speed gets enough time to mix with the digestive juices efficiently and consequently, the nutrients get into the body in large portions. As a result;

  • Energy is produced instantly
  • The body remains in a healthy condition
  • The body excretes waste perfectly
  • The immunity system strengthens

A condition known as Irritable bowel syndrome afflicts numerous people in America and the world at large. It results from imbalanced serotonin in your entrails. This condition is commonly a mental complication. Psychologists reason that the condition occurs due to mental instability which mostly results from stress. Since Kratom proves viability in reducing stress, such a condition is easily curable through the administration of Kratom.

A good mental state hugely contributes to how our body functions. In turn, if our body functions well, the metabolism also runs in the right way. Taking kratom also improves the stimulation of the serotonin receptors found on the walls of the gut. That leads to the production of balanced serotonin hence the condition gets under control.

When acid occurs in the stomach in excess, a lot of pain follows, and it also becomes uncomfortable to eat. That hugely affects your health since you lack enough nutrients to run your system. However, the good news is that Kratom can reduce excess acid in your body to a usable amount. That way, you can stomach food comfortably.